Prednisone and Cyclosporine in the Treatment of Severe Graves' Ophthalmopathy
Authors:
- Maarten Ph. MouritsMMMaarten Ph. Mourits
- Arie BerghoutABArie Berghout
- Eric P. KrenningEKEric P. Krenning
- Ruth van der GaagRGRuth van der Gaag
- Leo KoornneefLKLeo Koornneef
- Wilmar M. WiersingaWWWilmar M. Wiersinga
- 16 November 1989
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 321 (20) , 1353-1359
Abstract
It is uncertain what is the most appropriate medical therapy for patients with severe Graves' ophthalmopathy. Therefore, we carried out a single-blind, randomized clinical trial to compare the efficacy of prednisone with that of cyclosporine in 36 patients who had been euthyroid for at least two months. The two groups, each consisting of 18 patients, were similar in age, sex, and the duration and severity of ophthalmopathy.Keywords
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