Olfactory and taste dysfunction among mild‐to‐moderate symptomatic COVID‐19 positive health care workers: An international survey
Open Access
- 2 December 2020
- journal article
- research article
- Published by Wiley in Laryngoscope Investigative Otolaryngology
- Vol. 5 (6) , 1019-1028
Abstract
Objectives: To determine the prevalence of olfactory and taste dysfunction (OD; TD) among COVID‐19 positive health care workers (HCWs), their associated risk factors and prognosis.Methods: Between May and June 2020, a longitudinal multicenter study was conducted on symptomatic COVID‐19 PCR confirmed HCWs (COVID‐19 positive) in London and Padua.Results: Hundred and fourteen COVID‐19 positive HCWs were surveyed with a response rate of 70.6% over a median follow‐up period of 52 days. UK prevalence of OD and TD was 73.1% and 69.2%, respectively. There was a male to female ratio of 1:3 with 81.6% being white, 43.7% being nurses/health care assistants (HCAs), and 39.3% being doctors. In addition, 53.2% of them worked on COVID‐19 wards. Complete recovery was reported in 31.8% for OD and 47.1% for TD with a 52 days follow‐up. The job role of doctors and nurses negatively influenced smell (P = .04 and P = .02) and taste recovery (P = .02 and P = .01). Ethnicity (being white) showed to positively influence only taste recovery (P = .04). Sex (being female) negatively influenced OD and TD recovery only in Paduan HCWs (P = .02 and P = .011, respectively). Working on a COVID‐19 ward did not influence prognosis.Conclusions: The prevalence of OD and TD was considerably higher in HCWs. The prognosis for OD and TD recovery was worse for nurses/HCAs and doctors but working on a COVID‐19 ward did not influence prognosis. Sixty‐eight percent of surveyed HCWs at 52 days continued to experience OD or TD requiring additional future medical management capacity.Level of Evidence: 4.Keywords
This publication has 31 references indexed in Scilit:
- Presentation of New Onset Anosmia During the COVID-19 PandemicRhinology journal, 2020
- Isolated Sudden Onset Anosmia in COVID-19 Infection. A Novel Syndrome?Rhinology journal, 2020
- COVID‐19 and the Otolaryngologist: Preliminary Evidence‐Based ReviewThe Laryngoscope, 2020
- Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, ChinaJAMA, 2020
- Olfactory ensheathing cells from the nasal mucosa and olfactory bulb have distinct membrane propertiesJournal of Neuroscience Research, 2019
- Using a Three-Dimensional Collagen Matrix to Deliver Respiratory Progenitor Cells to Decellularized Trachea In VivoTissue Engineering Part C: Methods, 2019
- Epidemiology of smell and taste dysfunction2019
- Prognosis of Postviral Olfactory Loss: Follow-up Study for Longer than One YearAmerican Journal of Rhinology & Allergy, 2014
- Accuracy of Self‐Report in Detecting Taste DysfunctionThe Laryngoscope, 2008
- Neurogenesis and neuron regeneration in the olfactory system of mammals. I. Morphological aspects of differentiation and structural organization of the olfactory sensory neuronsJournal of Neurocytology, 1979