Nursing Management of Acute Complications Following rt-PA In Acute Ischemic Stroke

Authors:
  • JSJudith Spilker
    Judith Spilker
  • PBPatty Bratina
    Patty Bratina
  • SDSheila Daley
    Sheila Daley
  • RDRosario Donnarumma
    Rosario Donnarumma
  • SSSharion Sailor
    Sharion Sailor
  • JBJanet Braimah
    Janet Braimah
  • GKGail Kongable
    Gail Kongable
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Abstract
In the National Institutes of Neurologic Disorders and Stroke (NINDS) recombinant tissue plasminogen activator (rt-PA) stroke trial, the primary adverse events monitored were intracranial hemorrhage (ICH), systemic bleeding, death and new stroke. Nurses caring for the study patients noted these adverse events and other complications. In addition to what is known about acute ischemic stroke (AIS), the NINDS trial provides further information for optimal care of this specific group of patients. The complications found in this trial require expert nursing care to monitor, prevent and intervene, making clinical decisions relevant to the patients needs. The critical decision-making process must be grounded in knowledge of acute stroke physiology and thrombolysis.