Two New Verticillane-Type Diterpenoids from the Formosan Soft Coral Cespitularia hypotentaculata
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Open Access
- 1 January 2010
- journal article
- Published by Pharmaceutical Society of Japan in Chemical and Pharmaceutical Bulletin
- Vol. 58 (6) , 848-851
Abstract
Chemical investigations of the Formosan soft coral Cespitularia hypotentaculata ROXAS led to the isolation of two new verticillane diterpenoids, cespitularins R and S (1, 2), along with seven known compounds (3—9). The structures of these isolated compounds were elucidated on the basis of extensive spectroscopic analysis and by comparison with those of reported in literature. The anti-inflammatory activity using RAW 264.7 macrophages of compounds 1—9 were evaluated in vitro.Keywords
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