Spontaneous mutation by mutagenic repair of spontaneous lesions in DNA
Authors:
- 1 December 1976
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 264 (5588) , 719-722
Abstract
Strains of yeast carrying mutations in many of the steps in pathways repairing radiation-induced damage to DNA have enhanced spontaneous mutation rates. Most strains isolated because they have enhanced spontaneous mutation carry mutations in DNA repair systems. This suggests that much spontaneous mutation arises by mutagenic repair of spontaneous lesions.Keywords
This publication has 29 references indexed in Scilit:
- Further evidence for an inducible recombination repair system in Ustilago maydisMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1975
- Repair systems in SaccharomycesMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1974
- Specificity and frequency of ultraviolet-induced reversion of an iso-1-cytochrome c ochre mutant in radiation-sensitive strains of yeastJournal of Molecular Biology, 1974
- Synergistic interactions between rad mutations in yeastMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1973
- ULTRAVIOLET-INDUCED MUTATION AND DNA REPAIRAnnual Review of Microbiology, 1969
- The mutability toward ultarviolet light of recombination-deficient strains of Escherichia coliMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1969
- DNA RepairAnnual Review of Biochemistry, 1968
- Mutagenic DNA polymeraseBiochemical and Biophysical Research Communications, 1965
- Mutations in Barley Induced by X-Rays and RadiumScience, 1928
- Artificial Transmutation of the GeneScience, 1927