Evaluation of Hypoglycemia in Neonates of Women at Risk for Late Preterm Delivery: An Antenatal Late Preterm Steroids Trial Cohort Study
Open Access
- 27 May 2021
- journal article
- research article
- Published by Georg Thieme Verlag KG in American Journal of Perinatology
- Vol. 40 (05) , 532-538
Abstract
Objective In the antenatal late preterm steroids (ALPS) trial betamethasone significantly decreased short-term neonatal respiratory morbidity but increased the risk of neonatal hypoglycemia, diagnosed only categorically (72 hours was rare and similar in both groups, nine (2.4%, betamethasone) and four (1.9%, placebo, p = 0.18). Conclusion In this cohort, hypoglycemia was transient and most received no treatment, with a quicker resolution in the betamethasone group. Prolonged hypoglycemia was uncommon irrespective of steroid exposure. Key Points * Additional members of this network are listed in [ Supplementary Material ] (available in the online version). Received: 08 October 2020 Accepted: 16 March 2021 Article published online: 27 May 2021 © 2021. Thieme. All rights reserved. Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAKeywords
Funding Information
- NHLBI (HL098554)
- NHLBI (HL098354)
- NICHD (HD21410)
- NICHD (HD27915)
- NICHD (HD27917)
- NICHD (HD27869)
- NICHD (HD34116)
- NICHD (HD34208)
- NICHD (HD40485)
- NICHD (HD40500)
- NICHD (HD40512)
- NICHD (HD40544)
- NICHD (HD40545)
- NICHD (HD40560)
- NICHD (HD53097)
- NICHD (HD53118)
- NICHD (HD68268)
- NICHD (HD68258)
- NICHD (HD68282)
- NICHD (HD36801)
- National Center for Advancing Translational Sciences, National Institutes of Health (UL1 TR000040)
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