Optically Active 2,3‐Allenoates via Palladium‐Catalyzed Carbonylation of Enantioenriched Propargylic Mesylates
Authors:
- 22 February 2013
- journal article
- research article
- Published by Wiley in Advanced Synthesis & Catalysis
- Vol. 355 (4) , 741-750
Abstract
Under mild conditions, optically active 2,3‐allenoates were synthesized from enantioenriched propargylic mesylates with moderate to excellent yields and high efficiency of chirality transfer by using palladium(0) bis(dibenzylideneacetone) (3 mol%) with (S)‐(−)‐5,5′‐bis(diphenylphosphino)‐4,4′‐bi‐1,3‐benzodioxole [(S)‐SEGPHOS] (3 mol%) as the catalyst and diammonium hydrogen phosphate (1.1 equiv .) as the base.Keywords
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