Targeting epithelial-mesenchymal transition and apoptosis: novel histone methyltransferase inhibitors for colon cancer suppression
- 17 January 2026
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry
- Vol. 135, 118570
Abstract
No abstract availableKeywords
Funding Information
- Ministry of Education
- National Science and Technology Council (NSTC 112-2628-B-038-009-MY3)
- Taipei Medical University
This publication has 39 references indexed in Scilit:
- Molecular characterizations of nanodiamond and related carbon-based nanomaterials in the human cell line and zebrafish modelsDiamond and Related Materials, 2025
- Enhancing anti-cancer capacity: Novel class I/II HDAC inhibitors modulate EMT, cell cycle, and apoptosis pathwaysBioorganic & Medicinal Chemistry, 2024
- A novel HDAC1/2 inhibitor suppresses colorectal cancer through apoptosis induction and cell cycle regulationChemico-Biological Interactions, 2022
- Multiple myeloma driving factor WHSC1 is a transcription target of oncogene HMGA2 that facilitates colon cancer proliferation and metastasisBiochemical and Biophysical Research Communications, 2021
- Molecular subtypes of colorectal cancer: An emerging therapeutic opportunity for personalized medicineGenes & Diseases, 2021
- The Promise for Histone Methyltransferase Inhibitors for Epigenetic Therapy in Clinical Oncology: A Narrative ReviewAdvances in Therapy, 2020
- Dicoumarol suppresses HMGA2-mediated oncogenic capacities and inhibits cell proliferation by inducing apoptosis in colon cancerBiochemical and Biophysical Research Communications, 2020
- Identification of LEM-14 inhibitor of the oncoprotein NSD2Biochemical and Biophysical Research Communications, 2019
- Mutations of key driver genes in colorectal cancer progression and metastasisCancer and Metastasis Reviews, 2018
- Inhibition of H3K9 methyltransferase G9a induces autophagy and apoptosis in oral squamous cell carcinomaBiochemical and Biophysical Research Communications, 2015