Polystyrene Nanofiber Materials for Visible-Light-Driven Dual Antibacterial Action via Simultaneous Photogeneration of NO and O2(1Δg)
- 12 October 2015
- journal article
- research article
- Published by American Chemical Society (ACS) in ACS Applied Materials & Interfaces
- Vol. 7 (41) , 22980-22989
Abstract
This contribution reports on the preparation, characterization, and biological evaluation of electrospun polystyrene nanofiber materials engineered with a covalently grafted NO photodonor and ionically entangled tetracationic porphyrin and phthalocyanine photosensitizers. These photofunctional materials exhibit an effective and simultaneous photogeneration of two antibacterial species such as nitric oxide (NO) and singlet oxygen, O2(1Δg) under illumination with visible light, as demonstrated by their direct detection using amperometric and time-resolved spectroscopic techniques. Dual-mode photoantibacterial action is demonstrated by antibacterial tests carried out on Escherichia coli.Keywords
Funding Information
- Ministero dell'Istruzione, dell'Università e della Ricerca
- Czech Science Foundation (13-12496S)
This publication has 48 references indexed in Scilit:
- Virucidal Nanofiber Textiles Based on Photosensitized Production of Singlet OxygenPLOS ONE, 2012
- Light‐activated nanofibre textiles exert antibacterial effects in the setting of chronic wound healingExperimental Dermatology, 2012
- Antibacterial nanofiber materials activated by lightJournal of Biomedical Materials Research Part A, 2011
- Surface-functionalized electrospun nanofibers for tissue engineering and drug deliveryAdvanced Drug Delivery Reviews, 2009
- Photofunctional Polyurethane Nanofabrics Doped by Zinc Tetraphenylporphyrin and Zinc Phthalocyanine PhotosensitizersJournal of Fluorescence, 2009
- Hierarchical starch-based fibrous scaffold for bone tissue engineering applicationsJournal of Tissue Engineering and Regenerative Medicine, 2008
- Electrospinning: A Fascinating Method for the Preparation of Ultrathin FibersAngewandte Chemie International Edition, 2007
- Bactericidal nanofabrics based on photoproduction of singlet oxygenJournal of Materials Chemistry, 2006
- Surface modified nonwoven polysulphone (PSU) fiber mesh by electrospinning: A novel affinity membraneJournal of Membrane Science, 2006
- Electrospun nanofibrous structure: A novel scaffold for tissue engineeringJournal of Biomedical Materials Research, 2002