Genetic Characterization of Plasmid-Borne bla OXA-58 in Distinct Acinetobacter Species

Authors:

Abstract
Although the bla OXA-58 gene has been infrequently described in Brazil, contrasting with other bordering South American countries, we verified the maintenance of this resistance determinant over time among carbapenem-resistant Acinetobacter species isolates, not only in nosocomial settings but also in the environment. In addition, to the best of our knowledge, this is the first study to have used WPS analysis to evaluate the genetic surroundings of bla OXA-58 in Brazil. Moreover, the A. seifertii and A. baumannii clinical strains evaluated in this study were recovered 17 years apart in hospitals located in distinct Brazilian geographic regions.
Funding Information
  • MCTI | Conselho Nacional de Desenvolvimento Científico e Tecnológico (Process number 305535/2014-5)
  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (PhD Scholarship)
  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (PhD Scholarship)
  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (PhD Scholarship)
  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (PhD Scholarship)
  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Master Scholarship)

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