XANES spectroscopy for the clinician
Authors:
- Dominique BazinDBDominique Bazin
- Solenn ReguerSRSolenn Reguer
- Delphine VantelonDVDelphine Vantelon
- Jean-Philippe HaymannJHJean-Philippe Haymann
- Emmanuel LetavernierELEmmanuel Letavernier
- Vincent FrochotVFVincent Frochot
- Michel DaudonMDMichel Daudon
- Emmanuel EsteveEEEmmanuel Esteve
- Hester ColbocHCHester Colboc
- 1 September 2022
- journal article
- research article
- Published by MathDoc/Centre Mersenne in Comptes Rendus. Chimie
- Vol. 25 (S1) , 189-208
Abstract
XANES spectroscopy, which uses synchrotron radiation as a probe, offers substantial information about the local structure of biological samples, encompassing those without long range order such as Pt anticancer molecules, and nanometre scale or amorphous particles of calcium phosphate. Its subcellular spatial resolution, as well as its capacity to operate at room temperatures and pressures represent major advantages for medical research. Moreover, paraffin embedded biopsy samples can be analysed without any further preparation, Key publications which illustrate these capacities are presented.Keywords
This publication has 181 references indexed in Scilit:
- Microstructure, chemistry, and electronic structure of natural hybrid composites in abalone shellMicron, 2013
- X-ray Absorption Near Edge Structure Spectroscopy to Resolve the in Vivo Chemistry of the Redox-Active Indazoliumtrans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019)Journal of Medicinal Chemistry, 2013
- Prostatic Stones: Evidence of a Specific Chemistry Related to Infection and Presence of Bacterial ImprintsPLOS ONE, 2012
- The role of intracellular calcium phosphate in osteoblast-mediated bone apatite formationProceedings of the National Academy of Sciences, 2012
- Drug delivery systems: An updated reviewInternational Journal of Pharmaceutical Investigation, 2012
- PhosphorusK-edge XANES spectroscopy of mineral standardsJournal of Synchrotron Radiation, 2010
- Mechanisms of Cisplatin NephrotoxicityToxins, 2010
- Transient amorphous calcium phosphate in forming enamelJournal of Structural Biology, 2009
- The resurgence of platinum-based cancer chemotherapyNature Reviews Cancer, 2007
- Microcalcifications Associated with Breast Cancer: An Epiphenomenon or Biologically Significant Feature of Selected Tumors?Journal of Mammary Gland Biology and Neoplasia, 2005