Synthesis of pyrazolo[3,4‐b]pyridines using ammonium acetate as green reagent in multi‐component reactions
- 1 July 2008
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 45 (4) , 1221-1224
Abstract
Magnified image Several new pyrazolo[3,4‐b]pyridine derivatives were synthesized by one pot cyclocondensation of the components; 5‐amino‐3‐aryl‐1H‐phenylpyrazoles, p‐substituted benzoylacetonitriles and some aldehydes. The condensations were most effective by using ammonium acetate as the base catalyst; triethylamine was also studied as a catalyst.Keywords
This publication has 14 references indexed in Scilit:
- Synthesis of fused pyrimidines from amines and cyclic β-formylestersTetrahedron, 2007
- Controlled Microwave Heating in Modern Organic SynthesisAngewandte Chemie International Edition, 2004
- Microwave-assisted multi-component synthesis of fused 3-aminoimidazolesTetrahedron Letters, 2003
- Recent progress in the chemistry of multicomponent reactionsPure and Applied Chemistry, 2001
- Synthesis of novel pyrano fused quinolones, coumarins, and pyridonesJournal of Heterocyclic Chemistry, 1999
- Parallel synthesis of 3-aminoimidazo[1,2-a]pyridines and pyrazines by a new three-component condensationTetrahedron Letters, 1998
- Chemistry of Pyrazoles Condensed to Heteroaromatic Five- and Six-Membered Rings1990
- Chemistry of Pyrazolopyrimidines1987
- The Chemistry of Pyrazolopyridines1984
- Biologically Active PyraaolesJournal of Pharmaceutical Sciences, 1968