Improvement of the Intestinal Absorption of a Peptidomimetic, Boronic Acid Thrombin Inhibitor Possibly Utilizing the Oligopeptide Transporter

This publication has 14 references indexed in Scilit:

• New Inhibitors of Thrombin and Other Trypsin-like Proteases: Hydrogen Bonding of an Aromatic Cyano Group with a Backbone Amide of the P₁ Binding Site Replaces Binding of a Basic Side Chain
  Biochemistry, 1997
• Restricted Intestinal Absorption of Some β-Lactam Antibiotics by an Energy-Dependent Efflux System in Rat Intestine
  Pharmaceutical Research, 1997
• Molecular modeling study of structural requirements for the oligopeptide transporter
  Journal of Drug Targeting, 1996
• Intestinal Absorption Barriers and Transport Mechanisms, Including Secretory Transport, for a Cyclic Peptide, Fibrinogen Antagonist
  Pharmaceutical Research, 1996
• Challenges in the development of orally bioavailable thrombin active site inhibitors
  Blood Coagulation & Fibrinolysis, 1995
• Synthetic low-molecular weight thrombin inhibitors: molecular design and pharmacological profile
  Trends in Pharmacological Sciences, 1993
• Anticoagulant activity of a peptide boronic acid thrombin inhibitor by various routes of administration in rats
  Peptides, 1991
• Structural Requirements for the Intestinal Mucosal-Cell Peptide Transporter: The Need for N-Terminal α-Amino Group
  Pharmaceutical Research, 1991
• The selective inhibition of thrombin by peptides of boroarginine.
  Journal of Biological Chemistry, 1990
• H+ coupled transport of p.o. cephalosporins via dipeptide carriers in rabbit intestinal brush-border membranes: difference of transport characteristics between cefixime and cephradine.
  The Journal of Pharmacology and Experimental Therapeutics, 1988