Neonatal acute liver failure cases with echovirus 11 infections, Japan, August to November 2024

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Abstract
In 2022–23, several European countries reported paediatric acute liver failure (ALF) with enterovirus infection. In August–November 2024, three neonatal cases of ALF with echovirus 11 (E11) were reported in Tokyo, Japan. All neonates developed irreversible multiple-organ failure and died. The E11 strain belonged to the new lineage 1, which was the same as strains isolated from neonatal ALF cases in Europe in 2022–23.

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