Cardiovascular risk factors in 101 night shift and day workers in industry. A cross-sectional study
Authors:
- Marit SkogstadMSMarit Skogstad
- Sarah Msc AlsaediSASarah Msc Alsaedi
- Per Anton SirnesPSPer Anton Sirnes
- Asgeir MamenAMAsgeir Mamen
- Øivind SkareØSØivind Skare
- Elisabeth GoffengEGElisabeth Goffeng
- Lars Ole GoffengLGLars Ole Goffeng
- Dagfinn MatreDMDagfinn Matre
- Hans Christian Dalsbotten AassHAHans Christian Dalsbotten Aass
- Erika Zardin BrinchmannEBErika Zardin Brinchmann
Open Access
- 10 March 2026
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Occupational and Environmental Medicine
- Vol. 68 (9) , 756-765
Abstract
Objective: This cross-sectional study assesses cardiovascular disease (CVD) risk factors in industrial rotating night shift and day workers. Methods: We examined 27 day workers; 40 night shift workers with high and 34 with low night loads. We assessed sleep, blood pressure (BP), pulse wave velocity (PWV), carotid intima-media thickness (cIMT), maximal oxygen uptake (V̇O2max), glycosylated haemoglobin (HbA1c), lipids, focusing on inflammatory markers, and adipokines. Results: High load night shift workers had higher inflammation and lower adiponectin level compared to other shift workers and day workers. Night shifts of 8 and 12 hours shortened sleep. Number of night shifts was positively associated with inflammatory markers and negatively associated with adiponectin. Conclusions: Night shift work is associated with CVD risk factors. Shift schedules with fewer night shifts and longer recovery periods could mitigate it. ExportKeywords
Funding Information
- Borregaards Forsknings Fond
- Circle K Fond for Arbeidsmedisinsk forskning STI
This publication has 34 references indexed in Scilit:
- Investigating the relationship between shift work schedule and blood and metabolic parameters: a 10-years retrospective cohort studyScientific Reports, 2024
- The impact of adipokines on vascular networks in adipose tissueCytokine & Growth Factor Reviews, 2022
- Association between circulating cell adhesion molecules and risk of type 2 diabetes: A meta-analysisAtherosclerosis, 2019
- Sleep modulates haematopoiesis and protects against atherosclerosisNature, 2019
- Circadian aspects of adipokine regulation in rodentsBest Practice & Research Clinical Endocrinology & Metabolism, 2017
- Short sleep duration and health outcomes: a systematic review, meta-analysis, and meta-regressionSleep Medicine, 2017
- Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responsesScientific Reports, 2016
- Hyperglycemia and arterial stiffness: The Atherosclerosis Risk in the Communities studyAtherosclerosis, 2012
- Sleep loss and inflammationBest Practice & Research Clinical Endocrinology & Metabolism, 2010
- Increased levels of resistin in rotating shift workers: A potential mediator of cardiovascular risk associated with circadian misalignmentAtherosclerosis, 2010