PDE4 inhibition: a novel approach for the treatment of inflammatory bowel disease
Authors:
- Katharine H. BannerKBKatharine H. Banner
- Michael A. TrevethickMTMichael A. Trevethick
- 1 August 2004
- journal article
- review article
- Published by Elsevier in Trends in Pharmacological Sciences
- Vol. 25 (8) , 430-436
Abstract
No abstract availableKeywords
This publication has 51 references indexed in Scilit:
- Inflammatory bowel diseaseAlimentary Pharmacology & Therapeutics, 2003
- The Specific Type-4 Phosphodiesterase Inhibitor Mesopram Alleviates Experimental Colitis in MiceThe Journal of Pharmacology and Experimental Therapeutics, 2003
- Effect of Dexamethasone on the Metabonomics Profile Associated with Phosphodiesterase Inhibitor-Induced Vascular Lesions in RatsToxicology and Applied Pharmacology, 2002
- Interferon-? sensitizes colonic epithelial cell lines to physiological and therapeutic inducers of colonocyte apoptosisJournal of Cellular Physiology, 2000
- Dextran Sulfate Sodium-Induced Colonic Histopathology, but not Altered Epithelial Ion Transport, Is Reduced by Inhibition of Phosphodiesterase ActivityThe American Journal of Pathology, 2000
- Enhanced production of monocyte chemotactic protein 3 in inflammatory bowel disease mucosaGut, 1999
- Experimental colitis induced by dextran sulphate sodium in mice: beneficial effects of sulphasalazine and olsalazineAlimentary Pharmacology & Therapeutics, 1998
- Curative effects of phosphodiesterase 4 inhibitors in dextran sulfate sodium-induced colitis in the ratGastroenterology, 1998
- Review article: β3‐adrenoceptor agonists—future anti‐inflammatory drugs for the gastrointestinal tract?Alimentary Pharmacology & Therapeutics, 1996
- The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-α production by human mononuclear cellsInternational Journal of Immunopharmacology, 1993