Potassium Ion Release and Enzyme Secretion: Adrenergic Regulation by α-and β-Receptors

Authors:
Publisher website
Google Scholar
Abstract
Epinephrine caused amylase secretion and K + release in rat parotid slices. Propranolol, which blocks β-receptors, inhibited amylase secretion; phentolamine, which blocks α-receptors, inhibited K + release. Since enzyme secretion was associated with fusion of secretory granules to the cell membrane and K + release was associated with vacuole formation, it could be shown that both α- and β-receptors are present in the same exocrine cell. The findings appear to exclude cyclic 3′,5′-adenosine monophosphate as an intermediate in the α-receptor response.

This publication has 12 references indexed in Scilit: