Investigating the role of rostral pedunculopontine nucleus M4 receptors in motor deficits and dyskinesia in hemiparkinsonian rats
Authors:
- Nicole E. ChambersNCNicole E. Chambers
- Annique McLuneAMAnnique McLune
- Michael CoyleMCMichael Coyle
- Ashley CentnerACAshley Centner
- Jordan SergioJSJordan Sergio
- Isabella Del PrioreIPIsabella Del Priore
- Kathryn LanzaKLKathryn Lanza
- Craig W. LindsleyCLCraig W. Lindsley
- P. Jeffrey ConnPCP. Jeffrey Conn
- Christopher BishopCBChristopher Bishop
- 25 September 2025
- journal article
- Published by Elsevier in Behavioural Brain Research
- Vol. 496, 115847
Abstract
No abstract availableKeywords
Funding Information
- American Parkinson's Disease Foundation
- American Parkinson Disease Association
This publication has 58 references indexed in Scilit:
- Substantia Nigra Pars Reticulata Projections to the Pedunculopontine Nucleus Modulate DyskinesiaMovement Disorders, 2023
- Adaptive changes in striatal projection neurons explain the long duration response and the emergence of dyskinesias in patients with Parkinson’s diseaseJournal of Neural Transmission, 2022
- Pedunculopontine Nucleus Microstructure Predicts Postural and Gait Symptoms in Parkinson's DiseaseMovement Disorders, 2020
- The missing, the short, and the long: Levodopa responses and dopamine actionsAnnals of Neurology, 2017
- Brainstem control of locomotion and muscle tone with special reference to the role of the mesopontine tegmentum and medullary reticulospinal systemsJournal of Neural Transmission, 2015
- Transcription factors involved in the pathogenesis of L-DOPA-induced dyskinesia in a rat model of Parkinson's diseaseAmino Acids, 2002
- Frequency of levodopa‐related dyskinesias and motor fluctuations as estimated from the cumulative literatureMovement Disorders, 2001
- Multiplicity of muscarinic autoreceptor subtypes? Comparison of the distribution of cholinergic cells and cells containing mRNA for five subtypes of muscarinic receptors in the rat brainMolecular Brain Research, 1994
- Immunological localization of m1–m5 muscarinic acetylcholine receptors in peripheral tissues and brainLife Sciences, 1993
- Autoradiographic localization of M1 and M2 muscarine receptors in the rat brainNeuroscience, 1986