Measurements of cardiac output and organ blood flow in rats using 99Tcm labelled microspheres
Authors:
- Larsolof HafströmLHLarsolof Hafström
- Bertil PerssonBPBertil Persson
- Kaj SundqvistKSKaj Sundqvist
- 1 June 1979
- journal article
- research article
- Published by Wiley in Acta Physiologica Scandinavica
- Vol. 106 (2) , 123-128
Abstract
The cardiac output and regional blood flow have been simultaneously determined in the anesthetized rat by using the reference organ method. 99Tcm labelled dextran 15 μm microspheres were injected in the left ventricle while simultaneously an arterial reference sample was drawn at constant known rate. The values calculated regarding cardiac output agree well with previously recorded series. Regional organ blood flow in the rat is presented as ml. min‐1. g‐1 tissue and values do agree with those reported by others. The results indicate that the reference organ method can be used in the rat for the study of cardiac output and regional blood flow.Keywords
This publication has 24 references indexed in Scilit:
- Estimation of blood flow with radioactive tracersSeminars in Nuclear Medicine, 1976
- Measurement of cardiac output distribution using microspheres. Some practical and theoretical considerationsCardiovascular Research, 1974
- A Simple Radioactive Microsphere Method for Measuring Regional Flow and Cardiac OutputInvestigative Radiology, 1974
- Total and Regional Coronary Blood Flow Measured by Radioactive Microspheres in Conscious and Anesthetized DogsCirculation Research, 1969
- Studies of the Circulation with Radioactive MicrospheresInvestigative Radiology, 1969
- Validity Studies of the Radioactive Microsphere Method for the Study of the Distribution of Cardiac Output, Organ Blood Flow, and Resistance in the Conscious Rhesus MonkeyCardiovascular Research, 1969
- Measurement of Umbilical Arterial Blood Flow to the Sheep Placenta and Fetus in UteroCirculation Research, 1968
- Equations for Measuring Blood Flow by External Monitoring of RadioisotopesCirculation Research, 1965
- Effect of Hemorrhage on the Cardiac Output and Distribution in the RatCirculation Research, 1960
- THE NITROUS OXIDE METHOD FOR THE QUANTITATIVE DETERMINATION OF CEREBRAL BLOOD FLOW IN MAN: THEORY, PROCEDURE AND NORMAL VALUES 1Journal of Clinical Investigation, 1948