UMSCs Attenuate LPS/D-GalN-Induced Acute Liver Failure in Mice by Down-regulating the MyD88/NF-κB Pathway
Authors:
- Hailing LiaoHLHailing Liao
- Siying DuSDSiying Du
- Ting JiangTJTing Jiang
- Mengyao ZhengMZMengyao Zheng
- Zhao XiangZXZhao Xiang
- Jinhui YangJYJinhui Yang
Open Access
- 22 April 2021
- journal article
- research article
- Published by Xia & He Publishing in Journal of Clinical and Translational Hepatology
- Vol. 000 (000) , 000
Abstract
Acute liver failure (ALF) is an inflammatory process of acute liver cell injury. Mesenchymal stem cells (MSCs) are undifferentiated, primitive cells with anti-inflammatory, anti-apoptotic, and multi-directional differentiation abilities. This study aimed to explore the therapeutic mechanism of umbilical cord (U)MSCs in ALF.Keywords
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