New Classes of PDE7 Inhibitors Identified by a Fission Yeast-Based HTS
Authors:
- Arlene R. WymanAWArlene R. Wyman
- F. Douglas IveyFIF. Douglas Ivey
- Christina AllainCAChristina Allain
- Didem DemirbasDDDidem Demirbas
- Lili WangLWLili Wang
- Ozge CeyhanOCOzge Ceyhan
- Charles S. HoffmanCHCharles S. Hoffman
Open Access
- 1 April 2010
- journal article
- research article
- Published by Elsevier in SLAS Discovery
- Vol. 15 (4) , 359-367
Abstract
No abstract availableKeywords
This publication has 29 references indexed in Scilit:
- Synthesis, Structural Analysis, and Biological Evaluation of Thioxoquinazoline Derivatives as Phosphodiesterase 7 InhibitorsChemMedChem, 2009
- Cyclic nucleotide phosphodiesterase profiling reveals increased expression of phosphodiesterase 7B in chronic lymphocytic leukemiaProceedings of the National Academy of Sciences, 2008
- Development of a Fission Yeast-Based High-Throughput Screen to Identify Chemical Regulators of cAMP PhosphodiesterasesSLAS Discovery, 2008
- Schizosaccharomyces pombe Adenylate Cyclase Suppressor Mutations Suggest a Role for cAMP Phosphodiesterase Regulation in Feedback Control of Glucose/cAMP SignalingGenetics, 2005
- Compartmentalisation of phosphodiesterases and protein kinase A: opposites attractFEBS Letters, 2005
- Glucose sensing via the protein kinase A pathway in Schizosaccharomyces pombeBiochemical Society Transactions, 2005
- Identification of purine inhibitors of phosphodiesterase 7 (PDE7)Bioorganic & Medicinal Chemistry Letters, 2004
- Suppressors of an Adenylate Cyclase Deletion in the Fission Yeast Schizosaccharomyces pombeEukaryotic Cell, 2004
- Differential effects on TNFα production by pharmacological agents with varying molecular sites of actionInternational Journal of Immunopharmacology, 1997
- Fission yeast genes that confer resistance to staurosporine encode an AP-1-like transcription factor and a protein kinase related to the mammalian ERK1/MAP2 and budding yeast FUS3 and KSS1 kinases.Genes & Development, 1991