Cloning, sequence analysis and chromosome localization of a Drosophila muscarinic acetylcholine receptor
Authors:
- Michael G. FitzGeraldMFMichael G. FitzGerald
- Shoji ArakawaSAShoji Arakawa
- Jeannine D. GocayneJGJeannine D. Gocayne
- Deborah A. UrquhartDUDeborah A. Urquhart
- Linda M. HallLHLinda M. Hall
- Claire M. FraserCFClaire M. Fraser
- W.Richard McCombieWMW.Richard McCombie
- J.CRaig VenterJVJ.CRaig Venter
- 25 September 1989
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 255 (2) , 219-225
Abstract
Two cDNA clones (3.7 kb and 4.8 kb) encoding a Drosophila muscarinic acetylcholine receptor were isolated from a Drosophila head cDNA library and characterized by automated DNA sequence analysis. The Drosophila muscarinic receptor contains 788 amino acids with a calculated M r of 84 807 and displays greater than 60% homology with mammalian muscarinic receptors. The muscarinic receptor maps to the tip of the right arm of the second chromosome of the Drosophila genome.Keywords
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