Overcoming the novel glycan–lectin checkpoints in tumor microenvironments for the success of the cross-presentation-based immunotherapy

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Abstract
(a) Two primary mechanisms for cross-presentation of internalized antigens: cytosolic and vacuolar pathways. (b) To enhance antigen presentation and generate T cell responses, glycans are multivalently presented on a range of nanocarrier systems.
Funding Information
  • Japan Society for the Promotion of Science (JPJSBP120207716)
  • Department of Science and Technology, Ministry of Science and Technology, India (DST/INT/JSPS/P-307/2020)

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