Sized-fiber reflectometry for measuring local optical properties
Authors:
- S.A. PrahlSPS.A. Prahl
- 1 January 2001
- journal article
- Published by Institute of Electrical and Electronics Engineers (IEEE) in IEEE Journal of Selected Topics in Quantum Electronics
- Vol. 7 (6) , 952-958
Abstract
Sized-fiber spectroscopy describes a device and method for measuring absorption and reduced scattering properties of tissue using optical fibers with different diameters. The device used in this paper consists of two fibers with diameters of 200 and 600 /spl mu/m. Each fiber emits and collects its own backscattered light. Backscattered light measurements for solutions with absorption coefficients of 0.1-2.0 cm/sup -1/ and reduced scattering coefficients of 5-50 cm/sup -1/ demonstrate that the device is most sensitive for the highest scattering materials. Monte Carlo simulations suggest the device is insensitive to the fiber illumination characteristics and that the light returning to the fiber is nearly uniform over all directions. Finally, experiments and Monte Carlo simulations of the sized-fiber device indicate that 50% of the signal arises from roughly 1.2 and 1.9 reduced mean-free paths for the 200- and 600-/spl mu/m fibers, respectively.Keywords
This publication has 31 references indexed in Scilit:
- Design and testing of a white-light, steady-state diffuse reflectance spectrometer for determination of optical properties of highly scattering systemsApplied Optics, 1997
- Frequency-domain photon migration measurements of normal and malignant tissue optical properties in a human subjectApplied Optics, 1997
- A mathematical model for light dosimetry in photodynamic destruction of human endometriumPhysics in Medicine & Biology, 1996
- Absorption spectroscopy in tissue-simulating materials: a theoretical and experimental study of photon pathsApplied Optics, 1995
- Frequency-domain optical absorption spectroscopy of finite tissue volumes using diffusion theoryPhysics in Medicine & Biology, 1994
- Double-integrating-sphere system for measuring the optical properties of tissueApplied Optics, 1993
- Optical properties of intralipid: A phantom medium for light propagation studiesLasers in Surgery and Medicine, 1992
- Time resolved reflectance and transmittance for the noninvasive measurement of tissue optical propertiesApplied Optics, 1989
- Statistics of Penetration Depth of Photons Re-emitted from Irradiated TissueJournal of Modern Optics, 1989
- THE MEASUREMENT OF DIHEMATOPORPHYRIN ETHER CONCENTRATION IN TISSUE BY REFLECTANCE SPECTROPHOTOMETRYPhotochemistry and Photobiology, 1987