Hydroxychloroquine sulfate (“Plaquenil”) in treatment of rheumatoid arthritis
Authors:
- E. B. D. HamiltonEHE. B. D. Hamilton
- J. T. ScottJSJ. T. Scott
Open Access
- 1 October 1962
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 5 (5) , 502-512
Abstract
A controlled therapeutic trial in 41 patients comparing hydroxychloroquine (Plaquenil) and a placebo tablet showed a small but statistically significant difference in favor of hydroxychloroquine with regard to the number of analgesic tablets which the patients found it necessary to take in addition to the drug. Less significant differences, but still in favor of hydroxychloroquine, were found with various other methods of assessment. No serious toxic effects were encountered.Keywords
This publication has 15 references indexed in Scilit:
- Chloroquine and hydroxychloroyuine therapy in rheumatoid arthritisArthritis & Rheumatism, 1962
- Chloroquine Diphosphate in Rheumatoid ArthritisAnnals of the Rheumatic Diseases, 1961
- Chloroquine in Rheumatoid ArthritisAnnals of the Rheumatic Diseases, 1960
- AMODIAQUINE AND HYDROXYCHLOROQUINE IN RHEUMATOID ARTHRITISThe Lancet, 1959
- Controlled Trial of Physiotherapy in ArthritisBMJ, 1959
- A controlled study of chloroquine as an antirheumatic agentArthritis & Rheumatism, 1958
- Further Observations on the Use of 4-Aminoquinoline Compounds in Patients with Rheumatoid Arthritis or Related DiseasesCleveland Clinic Journal of Medicine, 1958
- IV. Comparison of Effects of Two Antimalarial Agents, Hydroxychloroquine Sulfate and Chloroquine Phosphate, in Patients with Rheumatoid ArthritisCleveland Clinic Journal of Medicine, 1957
- Chloroquine and Rheumatoid ArthritisAnnals of the Rheumatic Diseases, 1956
- THE DIFFERENTIAL SHEEP-CELL AGGLUTINATION TEST IN RHEUMATOID ARTHRITISThe Lancet, 1952