A multimodal atlas of hepatocellular carcinoma reveals convergent evolutionary paths and ‘bad apple’ effect on clinical trajectory
Open Access
- 21 May 2024
- journal article
- research article
- Published by Elsevier in Journal of Hepatology
- Vol. 81 (4) , 667-678
Abstract
No abstract availableKeywords
Funding Information
- Chinese Academy of Sciences (XDPB17)
- National Research Foundation Singapore (NRF-NRFF2015-04)
- National Research Foundation Singapore (NRF-NRFI08-2022)
- National Research Foundation Singapore (CRP23-2019-0072)
- National Medical Research Council (NMRC/CSA-SI/0018/2017)
- National Medical Research Council (NMRC/CIRG/1454/2016)
- National Medical Research Council (CIRG18may-0057)
- National Medical Research Council (NMRC/OFIRG/0064/2017)
- National Medical Research Council (NMRC/TCR/015-NCC/2016)
- National Medical Research Council (TCR/015-NCC/2016)
- National Medical Research Council (MOH-001067)
- Agency for Science, Technology and Research
- National Cancer Centre Singapore
- Ministry of Education - Singapore
- National Key Research and Development Program of China (2018YFC0910400)
- National Key Research and Development Program of China (2018YFC1406902)
- National Natural Science Foundation of China (92259303)
- National Natural Science Foundation of China (32293192/32293190)
- National Natural Science Foundation of China (31970566)
- National Natural Science Foundation of China (32000407)
This publication has 40 references indexed in Scilit:
- Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx RenalCell, 2018
- An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome AnalyticsCell, 2018
- Genomic and Functional Approaches to Understanding Cancer AneuploidyCancer Cell, 2018
- Comprehensive and Integrative Genomic Characterization of Hepatocellular CarcinomaCell, 2017
- Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trialThe Lancet, 2017
- The Molecular Signatures Database Hallmark Gene Set CollectionCell Systems, 2015
- High intratumor genetic heterogeneity is related to worse outcome in patients with head and neck squamous cell carcinomaCancer, 2013
- Transcriptome classification of HCC is related to gene alterations and to new therapeutic targetsHepatology, 2006
- Classification and prediction of survival in hepatocellular carcinoma by gene expression profilingHepatology, 2004
- A genetic model for colorectal tumorigenesisCell, 1990