Association of Longitudinal Trajectory of Albuminuria in Young Adulthood With Myocardial Structure and Function in Later Life

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Abstract
Albuminuria is a biomarker of endothelial dysfunction and has been associated with higher cardiovascular mortality among individuals with and without diabetes.1,2 Indeed, significant associations exist between albuminuria and incident heart failure (HF), stroke, myocardial infarction, and cardiovascular death among those without preexisting cardiovascular disease (CVD).3-5 Albuminuria may precede the onset of traditional CVD risk factors, as 70% of young adults with prevalent albuminuria have normotension and normoglycemia.6

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