Cannabinoids—Characteristics and Potential for Use in Food Production
Open Access
Abstract
Scientific demonstrations of the beneficial effects of non-psychoactive cannabinoids on the human body have increased the interest in foods containing hemp components. This review systematizes the latest discoveries relating to the characteristics of cannabinoids from Cannabis sativa L. var. sativa, it also presents a characterization of the mentioned plant. In this review, we present data on the opportunities and limitations of cannabinoids in food production. This article systematizes the data on the legal aspects, mainly the limits of Δ9-THC in food, the most popular analytical techniques (LC-MS and GC-MS) applied to assay cannabinoids in finished products, and the available data on the stability of cannabinoids during heating, storage, and access to light and oxygen. This may constitute a major challenge to their common use in food processing, as well as the potential formation of undesirable degradation products. Hemp-containing foods have great potential to become commercially popular among functional foods, provided that our understanding of cannabinoid stability in different food matrices and cannabinoid interactions with particular food ingredients are expanded. There remains a need for more data on the effects of technological processes and storage on cannabinoid degradation.Keywords
This publication has 141 references indexed in Scilit:
- The Endocannabinoid System, Cannabinoids, and PainRambam Maimonides Medical Journal, 2013
- Non‐THC cannabinoids inhibit prostate carcinoma growthin vitroandin vivo: pro‐apoptotic effects and underlying mechanismsBritish Journal of Pharmacology, 2012
- Enhanced Solubility, Stability, and Transcorneal Permeability of Delta-8-Tetrahydrocannabinol in the Presence of CyclodextrinsAAPS PharmSciTech, 2011
- Influence of Biopolymer Emulsifier Type on Formation and Stability of Rice Bran Oil‐in‐Water Emulsions: Whey Protein, Gum Arabic, and Modified StarchJournal of Food Science, 2011
- Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathwayFEBS Letters, 2009
- Cannabidiol displays unexpectedly high potency as an antagonist of CB1and CB2receptor agonistsin vitroBritish Journal of Pharmacology, 2007
- The Endocannabinoid System as an Emerging Target of PharmacotherapyPharmacological Reviews, 2006
- A rapid and simple procedure for the determination of cannabinoids in hemp food products by gas chromatography-mass spectrometryJournal of Pharmaceutical and Biomedical Analysis, 2005
- Pharmacokinetics and Pharmacodynamics of CannabinoidsClinical Pharmacokinetics, 2003
- Isolation, Structure, and Partial Synthesis of an Active Constituent of HashishJournal of the American Chemical Society, 1964