Uncovering the mechanisms that regulate tumor-induced T-cell anergy
Open Access
- 1 February 2013
- journal article
- Published by Taylor & Francis in OncoImmunology
- Vol. 2 (2) , e22679
Abstract
Helper T cells become hyporesponsive in the tumor microenvironment (at least in part) owing to the NFAT1-dependent expression of anergy-associated genes. Anergy constitutes a crucial mechanism to p...Keywords
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