Deletion of the Virion Host Shut-off Gene Enhances Neuronal-Selective Transgene Expression from an HSV Vector Lacking Functional IE Genes
Open Access
- 1 September 2017
- journal article
- Published by Elsevier in Molecular Therapy - Methods & Clinical Development
- Vol. 6, 79-90
Abstract
No abstract availableKeywords
Funding Information
- NIH (NS064988, DK044935)
- CHDI Foundation (A3777, A8790)
- Commonwealth of Pennsylvania (SAP #4100061184)
- European Community (FP7-PEOPLE-2011-IAPP project 285827 [EPIXCHANGE])
- Italian Ministry for Education, University and Research (PRIN project 2010N8PBAA [INBDNF])
This publication has 46 references indexed in Scilit:
- Regulation of alphaherpesvirus infections by the ICP0 family of proteinsJournal of General Virology, 2013
- The Herpes Simplex Virus 1 vhs Protein Enhances Translation of Viral True Late mRNAs and Virus Production in a Cell Type-Dependent MannerJournal of Virology, 2011
- HSV Delivery of a Ligand-regulated Endogenous Ion Channel Gene to Sensory Neurons Results in Pain Control Following Channel ActivationMolecular Therapy, 2011
- A Double Mutation in Glycoprotein gB Compensates for Ineffective gD-Dependent Initiation of Herpes Simplex Virus Type 1 InfectionJournal of Virology, 2010
- Optimal promoter usage for lentiviral vector-mediated transduction of cultured central nervous system cellsJournal of Neuroscience Methods, 2010
- Epigenetic Modulation of Gene Expression from Quiescent Herpes Simplex Virus GenomesJournal of Virology, 2009
- Herpes Vector–mediated Gene Transfer in the Treatment of Chronic PainMolecular Therapy, 2009
- Herpes Simplex Virus Virion Host Shutoff Attenuates Establishment of the Antiviral StateJournal of Virology, 2008
- Latency associated promoter transgene expression in the central nervous system after stereotaxic delivery of replication-defective HSV-1-based vectorsGene Therapy, 2001
- Efficient Activation of Viral Genomes by Levels of Herpes Simplex Virus ICP0 Insufficient To Affect Cellular Gene Expression or Cell SurvivalJournal of Virology, 2001