Loss of Asxl1 leads to myelodysplastic syndrome–like disease in mice
Authors:
Open Access
- 23 January 2014
- journal article
- research article
- Published by American Society of Hematology in Blood
- Vol. 123 (4) , 541-553
Abstract
Key Points: Deletion/haploinsufficiency of Asxl1 causes MDS-like disease in mice. Asxl1 loss reduces the HSC pool and decreases HSC hematopoietic repopulating capacity in vivo.Keywords
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