The Inhibition of the l-Histidine Decarboxylases of Guinea-Pig Kidney and Rat Hepatoma

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Abstract
The preparation of some potential inhibitors of l-histidine decarboxylase is described. These, and certain commercially available compounds, have been compared for their ability to inhibit in vitro the histidine decarboxylases of guinea-pig kidney and of the transplantable rat hepatoma (F-Hep). Structure-activity relationships of these inhibitors are discussed.

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