Design, synthesis and evaluation of azaacridine derivatives as dual-target EGFR and Src kinase inhibitors for antitumor treatment

This publication has 50 references indexed in Scilit:

• Tamoxifen has a proliferative effect in endometrial carcinoma mediated via the GPER/EGFR/ERK/cyclin D1 pathway: A retrospective study and an in vitro study
  Molecular and Cellular Endocrinology, 2016
• Gallic acid abolishes the EGFR/Src/Akt/Erk-mediated expression of matrix metalloproteinase-9 in MCF-7 breast cancer cells
  Chemico-Biological Interactions, 2016
• Design and discovery of 4-anilinoquinazoline-acylamino derivatives as EGFR and VEGFR-2 dual TK inhibitors
  European Journal of Medicinal Chemistry, 2016
• Investigating molecular dynamics-guided lead optimization of EGFR inhibitors
  Bioorganic & Medicinal Chemistry, 2016
• In vitro baselining of new pyrrolopyrimidine EGFR-TK inhibitors with Erlotinib
  European Journal of Pharmaceutical Sciences, 2015
• Target Modulation by a Kinase Inhibitor Engineered to Induce a Tandem Blockade of the Epidermal Growth Factor Receptor (EGFR) and c-Src: The Concept of Type III Combi-Targeting
  PLOS ONE, 2015
• Epidermal growth factor receptor mutations in lung cancer
  Nature Reviews Cancer, 2007
• The epidermal growth factor receptor family
  Endocrine-Related Cancer, 2005
• EGFR-induced cell migration is mediated predominantly by the JAK-STAT pathway in primary esophageal keratinocytes
  American Journal of Physiology-Gastrointestinal and Liver Physiology, 2004
• Epidermal Growth Factor Receptor in Non–Small-Cell Lung Carcinomas: Correlation Between Gene Copy Number and Protein Expression and Impact on Prognosis
  Journal of Clinical Oncology, 2003