Minimally invasive surgery to treat embryonal tumors of childhood
- 5 December 2019
- journal article
- review article
- Published by Springer Nature in Cancer and Metastasis Reviews
- Vol. 38 (4) , 695-708
Abstract
Minimally invasive surgery (MIS) to resect primary and metastatic pediatric embryonal tumors offers the potential for reduced postoperative morbidity with smaller wounds, less pain, fewer surgical site infections, decreased blood loss, shorter hospital stays, and less disruption to treatment regimens. However, significant controversy surrounds the question of whether a high-fidelity oncologic resection of childhood embryonal tumors with gross total resection, negative margins, and appropriate lymph node sampling can be achieved through MIS. This review outlines the diverse applications of MIS to treat definitively pediatric embryonal malignancies, including this approach to metastatic deposits. It outlines specific patient populations and presentations that may be particularly amenable to the minimally invasive approach. This work further summarizes the current evidence supporting the efficacy of MIS to accomplish a definitive, oncologic resection without compromising relapse-free or overall survival. Finally, the review offers technical considerations to consider in order to achieve a safe and complete resection.Keywords
This publication has 28 references indexed in Scilit:
- Minimally Invasive versus Abdominal Radical Hysterectomy for Cervical CancerNew England Journal of Medicine, 2018
- Genetic Predisposition to NeuroblastomaChildren, 2018
- Oncologic outcomes after robot‐assisted versus laparoscopic distal pancreatectomy: Analysis of the National Cancer DatabaseJournal of Surgical Oncology, 2018
- Maintaining oncologic integrity with minimally invasive resection of pediatric embryonal tumorsSurgery, 2018
- Evolving application of minimally invasive cancer operations at a tertiary cancer centerJournal of Surgical Oncology, 2017
- Impact of Extent of Resection on Local Control and Survival in Patients From the COG A3973 Study With High-Risk NeuroblastomaJournal of Clinical Oncology, 2017
- Family history of cancer and childhood rhabdomyosarcoma: a report from the Children's Oncology Group and the Utah Population DatabaseCancer Medicine, 2015
- Minimally invasive surgery of neuroblastic tumors in children: Indications depend on anatomical location and image‐defined risk factorsPediatric Blood & Cancer, 2014
- Clinical outcomes in children with adrenal neuroblastoma undergoing open versus laparoscopic adrenalectomyJournal of Pediatric Surgery, 2013
- Laparoscopic Resection of Abdominal NeuroblastomaAnnals of Surgical Oncology, 2007