A facile three-component [3+2]-cycloaddition for the regioselective synthesis of highly functionalised dispiropyrrolidines acting as antimycobacterial agents
Authors:
- Ang Chee WeiAng Chee Wei
- Mohamed Ashraf AliMAMohamed Ashraf Ali
- Yeong Keng YoonYeong Keng Yoon
- Rusli IsmailRusli Ismail
- Tan Soo ChoonTCTan Soo Choon
- Raju Suresh KumarRaju Suresh Kumar
- 1 March 2013
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 23 (5) , 1383-1386
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- Synthesis, molecular modeling and biological evaluation of chalcone thiosemicarbazide derivatives as novel anticancer agentsEuropean Journal of Medicinal Chemistry, 2011
- Identification of novel antitubercular compounds through hybrid virtual screening approachBioorganic & Medicinal Chemistry, 2010
- Tuberculosis drug development: Progress, challenges, and the road aheadTuberculosis, 2010
- Synthesis and biological evaluation of nitrogen-containing benzophenone analogues as TNF-α and IL-6 inhibitors with antioxidant activityBioorganic & Medicinal Chemistry Letters, 2010
- A highly atom economic, chemo-, regio- and stereoselective synthesis and evaluation of spiro-pyrrolothiazoles as antitubercular agentsBioorganic & Medicinal Chemistry Letters, 2010
- A facile synthesis and antimycobacterial evaluation of novel spiro-pyrido-pyrrolizines and pyrrolidinesEuropean Journal of Medicinal Chemistry, 2009
- Discovery of Antimycobacterial Spiro-piperidin-4-ones: An Atom Economic, Stereoselective Synthesis, and Biological InterventionJournal of Medicinal Chemistry, 2008
- IntroductionTuberculosis, 2008
- Hydrogen Peroxide-Mediated Isoniazid Activation Catalyzed by Mycobacterium tuberculosis Catalase−Peroxidase (KatG) and Its S315T Mutant,Biochemistry, 2006
- 4-dimethylamino-3′,4′-dimethoxychalcone downregulates iNOS expression and exerts anti-inflammatory effectsFree Radical Biology and Medicine, 2001