Association of HLA-A9 and HLA-B5 with Buerger's disease.

Authors:
  • GMG A McLoughlin
    G A McLoughlin
  • CHC R Helsby
    C R Helsby
  • CEC C Evans
    C C Evans
  • DCD M Chapman
    D M Chapman

Abstract
Eighteen patients who satisfied stringent criteria for the diagnosis of Buerger's disease, healthy controls, and patients with atherosclerosis were tested for various HLA antigens. The incidence of HLA-A9 and HLA-B5 was significantly greater among those with Buerger's disease. This finding supports the concept that Buerger's disease is a distinct clinicopathological condition.