Gold Nanoparticle-Biological Molecule Interactions and Catalysis
Open Access
Abstract
This review gives a brief summary of the field of gold nanoparticle interactions with biological molecules, particularly those with possible catalytic relevance. Gold nanoparticles are well known as catalysts in organic chemistry but much is unknown regarding their potential as catalysts of reactions involving biological molecules such as protein and nucleic acids. Biological molecules may be the substrate for catalysis or, if they are the ligand coating the gold particle, may be the catalyst itself. In other cases biological molecules may form a template upon which gold nanoparticles can be precisely arrayed. As relatively little is currently known about the catalytic capabilities of gold nanoparticles in this area, this review will consider templating in general (including, but not restricted to, those which result in structures having potential as catalysts) before going on to consider firstly catalysis by the gold nanoparticle itself followed by catalysis by ligands attached to gold nanoparticles, all considered with a focus on biological molecules.Keywords
This publication has 145 references indexed in Scilit:
- pH Control of the Electrostatic Binding of Gold and Iron Oxide Nanoparticles to Tobacco Mosaic VirusLangmuir, 2013
- Update on selective oxidation using goldChemical Society Reviews, 2011
- Getting Past the RNA World: The Initial Darwinian AncestorCold Spring Harbor Perspectives in Biology, 2010
- Pyramidal and Chiral Groupings of Gold Nanocrystals Assembled Using DNA ScaffoldsJournal of the American Chemical Society, 2009
- Highly Sensitive and Selective Colorimetric Sensors for Uranyl (UO22+): Development and Comparison of Labeled and Label-Free DNAzyme-Gold Nanoparticle SystemsJournal of the American Chemical Society, 2008
- Noninvasive radiofrequency ablation of cancer targeted by gold nanoparticlesSurgery, 2008
- Utilisation of plant viruses in bionanotechnologyOrganic & Biomolecular Chemistry, 2007
- Two-Dimensional Nanoparticle Arrays Show the Organizational Power of Robust DNA MotifsNano Letters, 2006
- Type II restriction endonucleases: structure and mechanismCellular and Molecular Life Sciences, 2005
- Regulatory Features of the trp Operon and the Crystal Structure of the trp RNA-binding Attenuation Protein from Bacillus stearothermophilusJournal of Molecular Biology, 1999