A Heterogeneous‐Catalyst‐Based, Microwave‐Assisted Protocol for the Synthesis of 2,2′‐Bipyridines
Authors:
- 26 May 2008
- journal article
- research article
- Published by Wiley in Chemistry – An Asian Journal
- Vol. 3 (6) , 1046-1049
Abstract
A new method of preparing 2,2′‐bipyridines with short reaction times by using microwave assistance and heterogeneous catalysts has been developed. With a Negishi‐like protocol, it was found that Ni/Al2O3–SiO2 afforded 2,2′‐bipyridine products in up to 86 % yield in 1 h. Palladium supported on alumina also provided yields of 2,2′‐bipyridines comparable to those seen for homogeneous PEPPSITM (1,3‐diisopropylimidazol‐2‐ylidene)(3‐chloropyridyl)palladium(II)dichloride) and tetrakis(triphenylphosphanyl)palladium complexes.Keywords
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