Subtle Neurological Abnormalities as Risk Factors for Cognitive and Functional Decline, Cerebrovascular Events, and Mortality in Older Community-Dwelling Adults
Authors:
- Marco InzitariMIMarco Inzitari
- Claudia PozziCPClaudia Pozzi
- Luigi FerrucciLFLuigi Ferrucci
- Daniela ChiarantiniDCDaniela Chiarantini
- Lucio A. RinaldiLRLucio A. Rinaldi
- Marco BacciniMBMarco Baccini
- Riccardo PiniRPRiccardo Pini
- Giulio MasottiGMGiulio Masotti
- Niccolò MarchionniNMNiccolò Marchionni
- Mauro Di BariMBMauro Di Bari
Open Access
- 23 June 2008
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 168 (12) , 1270-1276
Abstract
Studies of apparently healthy, older community-dwelling persons have shown that subclinical diseases of different organs are associated with poor physical performance1,2 and frailty.3 In the Cardiovascular Health Study (CHS),4 a lower extent of subclinical cardiovascular disease predicted successful aging, defined as the years lived without physical and cognitive impairment, overt cardiovascular disease, cancer, and chronic obstructive pulmonary disease.Keywords
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