Lithium Bromide as a Mild, Efficient, and Recyclable Catalyst for the One-Pot Synthesis of Tetrahydro-4H-Chromene Derivatives in Aqueous Media
Authors:
- 2 February 2010
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 40 (4) , 587-594
Abstract
A simple, efficient, one-pot method has been developed for the synthesis of tetrahydro-4H-chromene derivatives by concurrent reaction of aryl aldehydes, active methylene compounds, and 1,3-cyclohexanedins using a catalytic amount of lithium bromide in aqueous media. The present approach offers several advantages such as shorter reaction times, good yields, low cost, recycling of the catalyst, and simple workup.Keywords
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