Individual utilization of anti‐asthma medication by young adults: a prescription database analysis
Authors:
- 1 July 1993
- journal article
- Published by Wiley in Journal of Internal Medicine
- Vol. 234 (1) , 65-70
Abstract
Objectives. To analyse and evaluate current practice of asthma therapy by use of computerized prescription data.Design. Descriptive, non‐interventive.Setting. A pharmacoepidemiological database on computerized refund claims from pharmacies in the Odense region in Denmark.Subjects. Persons aged 20–44, presenting prescriptions for asthma drugs during the period 1 October 1990 to 30 September 1991.Main outcome measures. Prevalence of asthma drug use, the regimes chosen, relationship between β‐agonist and steroid use by the individual patient.Results. In all, 3020 persons used anti‐asthma drugs, corresponding to a crude 1‐year prevalence of 3.6%. Sixty per cent were women. The subjects had an average anti‐asthma drug consumption corresponding to 86% of the population's average. The four most common regimes were inhaled β‐agonist monotherapy, inhaled β‐agonist and corticosteroid, oral β‐agonist monotherapy and inhaled corticosteroid monotherapy, altogether accounting for 79% of users. The proportion of corticosteroid users increased with increasing individual use of β‐agonists. With an annual β‐agonist purchase of 100–200 defined daily doses, still less than half also used steroids.Conclusion. The majority of patients use a regime agreeing with current guidelines, except that more patients should be prescribed corticosteroids. The observed large increase in asthma drug use is likely to be explained by an intensified treatment of individual patients, rather than an increased prevalence.Keywords
This publication has 15 references indexed in Scilit:
- Influence of ß-Adrenergic Receptor Function during Terbutaline Treatment on Allergen Sensitivity and Bronchodilator Response to Terbutaline in Asthmatic SubjectsChest, 1992
- The Use of β-Agonists and the Risk of Death and near Death from AsthmaNew England Journal of Medicine, 1992
- Regular inhaled beta-agonist treatment in bronchial asthmaThe Lancet, 1990
- Effect of Long-term Treatment with an Inhaled Corticosteroid (Budesonide) on Airway Hyperresponsiveness and Clinical Asthma in Nonsteroid-dependent AsthmaticsAmerican Review of Respiratory Disease, 1990
- Case-control study of prescribed fenoterol and death from asthma in New Zealand, 1977-81.Thorax, 1990
- Prevalence and treatment of asthma in the Michigan Medicaid patient population younger than 45 years, 1980–1986Journal of Allergy and Clinical Immunology, 1989
- Asthma drug therapy trends in the United States, 1972 to 1985Journal of Allergy and Clinical Immunology, 1987
- HAS THE MANAGEMENT OF ASTHMA IMPROVED?The Lancet, 1987
- Trends in sales of drugs for asthma in New Zealand, Australia, and the United Kingdom, 1975-81.BMJ, 1984
- Mortality from asthma: a new epidemic in New ZealandBMJ, 1982