Remission in Dermatitis Herpetiformis
Authors:
- Seth M. SteinbergSSSeth M. Steinberg
- Stephen I. KatzSKStephen I. Katz
Open Access
- 1 March 2011
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 147 (3) , 301-305
Abstract
Dermatitis herpetiformis (DH), also known as Duhring-Brocq disease, is an autoimmune blistering skin disease that manifests as pruritic papules and vesicles and is associated with celiac disease.1 Dermatitis herpetiformis is diagnosed by characteristic clinical and histopathologic findings and the presence of granular IgA deposits at the dermoepidermal junction of uninvolved skin. Histopathologic characteristics include microabscesses or subepidermal blisters with neutrophilic infiltrates at dermal papillary tips.2 The skin lesions respond to sulfone or sulfapyridine therapy and to strict restriction of gluten from the diet.3,4 Diseases associated with DH include celiac disease, autoimmune thyroid disease, and pernicious anemia.5Keywords
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