Pechmann Reaction Promoted by Boron Trifluoride Dihydrate
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Open Access
- 31 August 2005
- Vol. 10 (7) , 762-766
Abstract
The Pechmann reaction of substituted phenols 1a-e with methyl acetoacetate (2) can be activated by boron trifluoride dihydrate (3) to give the corresponding 4-methyl- coumarin derivatives 4a-e in excellent yield (98-99 %).Keywords
This publication has 20 references indexed in Scilit:
- The Pechmann ReactionJournal of Chemical Education, 1998
- Acceleration of the Pechmann Reaction by Microwave Irradiation: Application to the Preparation of Coumarins†Journal of Chemical Research, 1997
- Convenient Preparation of Alkyl Nitrates Free of Nitrites with Potassium Nitrate and Boron Trifluoride HydrateSynthesis, 1993
- Aromatic Nitration with Potassium Nitrate or Nitric Acid and Boron Trifluoride MonohydrateSynthesis, 1992
- Boron Trifluoride Monohydrate Catalyzed One-Flask Preparation of Sulfides from Carbonyl Compounds with Thiols and TriethylsilaneSynthesis, 1992
- Chemistry in superacids. 8. Superacid-catalyzed carbonylation of methane, methyl halides, methyl alcohol, and dimethyl ether to methyl acetate and acetic acidThe Journal of Organic Chemistry, 1990
- The Solubilization Equilibrium of 7-Ethoxycoumarins in Ionic MicellesBulletin of the Chemical Society of Japan, 1988
- Ionic hydrogenations using boron trifluoride hydrate. Reductions of polycyclic aromaticsThe Journal of Organic Chemistry, 1979
- The crystal structure of boron trifluoride dihydrateActa Crystallographica, 1964
- Die Molekülverbindungen des Borfluorids mit dem Wasser, den Alkoholen und den organischen SäurenJournal für Praktische Chemie, 1934