Mixed Lymphocyte Cultures Produce Effector Cells: Model in vitro for Allograft Rejection
- 3 April 1970
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 168 (3927) , 133-135
Abstract
Mouse peripheral lymphocytes sensitized in vitro by culturing with allogeneic lymphocytes produced immunospecific destruction of target cells, as measured by release of chromium-51. Thus the sensitizing and effector phases of the cell-bound immune response can both be studied in an in vitro system.Keywords
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