MATERNAL THYROID HORMONE LEVELS IN PREGNANCY AND THE SUBSEQUENT COGNITIVE AND MOTOR PERFORMANCE OF THE CHILDREN
Authors:
- 1 September 1984
- journal article
- research article
- Published by Wiley in Clinical Endocrinology
- Vol. 21 (3) , 265-270
Abstract
Serum levels of thyroxine [T4] and triiodothyronine [T3] during pregnancy were measured in women from a severely iodine deficient region in the highlands of Papua New Guinea. Subsequently the children born to these women were examined when aged 10-12 yr and measures made of intellectual ability and motor competence. A significant correlation between these measures in the children and the maternal T4 but not maternal T3 level was observed. Maternal T4 and not T3 may be essential for normal neurological maturation of the fetus before the fetal thyroid becomes functional.Keywords
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