8-oxo-7,8-dihydroguanosine (8-oxo-Guo) drives platelet inflammatory signaling pathways via toll-like receptors
Authors:
- Jia-Xin PanJPJia-Xin Pan
- Rui LiRLRui Li
- Gang ShengGSGang Sheng
- Ruo-Mei QiRuo-Mei Qi
- 20 May 2026
- journal article
- Published by Elsevier in Free Radical Biology and Medicine
- Vol. 253, 257-271
Abstract
No abstract availableKeywords
Funding Information
- National Key Research and Development Program of China (2024YFA1109102)
- National Natural Science Foundation of China (82304565)
- Chinese Academy of Medical Sciences (2021-I2M-1 -050)
- Beijing Hospital
This publication has 34 references indexed in Scilit:
- Platelets in Thrombosis and AtherosclerosisThe American Journal of Pathology, 2024
- ICAM-1 and VCAM-1: Gatekeepers in various inflammatory and cardiovascular disordersClinica Chimica Acta, 2023
- Rapid extraction and analysis of oxidative stress and DNA damage biomarker 8-hydroxy-2′-deoxyguanosine (8-OHdG) in urine: Application to a study with pregnant womenInternational Journal of Hygiene and Environmental Health, 2023
- 8-Oxoguanine: from oxidative damage to epigenetic and epitranscriptional modificationExperimental & Molecular Medicine, 2022
- Urinary 8-oxo-7,8-dihydroguanosine as a potential biomarker of frailty for elderly patients with cardiovascular diseaseFree Radical Biology and Medicine, 2020
- Interplay of Guanine Oxidation and G-Quadruplex Folding in Gene PromotersJournal of the American Chemical Society, 2019
- Assessment of RANTES levels as the indicators of plaque vulnerability in rabbit models of atherosclerosisPathology - Research and Practice, 2014
- Crosstalk of reactive oxygen species and NF-κB signalingCell Research, 2010
- Increased Platelet Surface Expression of P-Selectin and Thrombospondin as Markers of Platelet Activation in Essential ThrombocythaemiaThrombosis Research, 1999
- Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent plateletsNature, 1992