Using Cell-to-Cell Variability—A New Era in Molecular Biology
- 27 April 2012
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 336 (6080) , 425-426
Abstract
Studying the phenotypic differences between genetically identical cells rather than their general features can reveal novel regulatory mechanisms for diverse cellular processes.Keywords
This publication has 23 references indexed in Scilit:
- Single‐cell analysis of population context advances RNAi screening at multiple levelsMolecular Systems Biology, 2012
- We are all individuals: causes and consequences of non-genetic heterogeneity in mammalian cellsCurrent Opinion in Genetics & Development, 2011
- A Fluorescent Reporter of AMPK Activity and Cellular Energy StressCell Metabolism, 2011
- Cell-to-Cell Variability in PI3K Protein Level Regulates PI3K-AKT Pathway Activity in Cell PopulationsCurrent Biology, 2011
- Origins of regulated cell-to-cell variabilityNature Reviews Molecular Cell Biology, 2011
- Single-cell NF-κB dynamics reveal digital activation and analogue information processingNature, 2010
- Cellular Heterogeneity: Do Differences Make a Difference?Cell, 2010
- Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosisNature, 2009
- Determination of cell fate selection during phage lambda infectionProceedings of the National Academy of Sciences, 2008
- Nature, Nurture, or Chance: Stochastic Gene Expression and Its ConsequencesCell, 2008