The new UK Medical Eligibility Criteria for Contraceptive Use (UKMEC) 2025: what has changed?

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Abstract
Updates have been made to conditions with increased risk of thrombosis and use of depot medroxyprogesterone acetate (DMPA). Four medical categories—multiple risk factors for venous thromboembolism (VTE), multiple sclerosis (MS), chronic kidney disease (CKD) and sickle cell trait (SCT)—have also been added. Guidance on levonorgestrel intrauterine device (LNG-IUD) use and the risk of stroke, and consideration regarding anxiety and mood disorders and hormonal contraception (HC), feature in the 2025 UKMEC.
Funding Information
  • CoSRH Clinical Effectiveness Unit (Not applicable)

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