High Prevalence of Coinfecting Enteropathogens in Suspected Rotavirus Vaccine Breakthrough Cases
Open Access
- 18 November 2021
- journal article
- research article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 59 (12) , e0123621
Abstract
Despite the global use of rotavirus vaccines, vaccine breakthrough cases remain a pediatric health problem. In this study, we investigated suspected rotavirus vaccine breakthrough cases using next-generation sequencing (NGS)-based viral metagenomics ( n = 102) and a panel of semiquantitative reverse transcription-PCR (RT-qPCR) ( n = 92) targeting known enteric pathogens.Keywords
This publication has 82 references indexed in Scilit:
- ViPR: an open bioinformatics database and analysis resource for virology researchNucleic Acids Research, 2011
- The Sequence Alignment/Map format and SAMtoolsBioinformatics, 2009
- Fast and accurate short read alignment with Burrows–Wheeler transformBioinformatics, 2009
- Are Human P[14] Rotavirus Strains the Result of Interspecies Transmissions from Sheep or Other Ungulates That Belong to the Mammalian Order Artiodactyla ?Journal of Virology, 2009
- New Insights on Classification, Identification, and Clinical Relevance ofBlastocystissppClinical Microbiology Reviews, 2008
- Recommendations for the classification of group A rotaviruses using all 11 genomic RNA segmentsArchives of Virology, 2008
- Analyzing real-time PCR data by the comparative CT methodNature Protocols, 2008
- jModelTest: Phylogenetic Model AveragingMolecular Biology and Evolution, 2008
- Database resources of the National Center for Biotechnology InformationNucleic Acids Research, 2006
- MUSCLE: multiple sequence alignment with high accuracy and high throughputNucleic Acids Research, 2004