Opioid Overdose After Medication for Opioid Use Disorder Initiation Following Hospitalization or ED Visit
Authors:
Open Access
- 1 July 2024
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Network Open
- Vol. 7 (7) , e2423954
Abstract
Opioid-related hospitalizations in the US have increased markedly in the past several years, from 136.8 per 100 000 population in 2005 to 250.4 per 100 000 population in 2020.1 Hospitalizations related to opioid use disorder (OUD) comprised about 3.4% of all hospitalizations in metropolitan areas in 2016.2 These hospitalizations are not always related to overdose but rather to the spectrum of morbidity that accompanies substance use, including HIV infection, hepatitis, endocarditis, skin and soft tissue infections, and bacteremia.3 Opioid-related complications contribute disproportionately to deaths associated with sepsis in younger patients.4Keywords
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